Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27519798 | 1.00 | ABCB1 (0.53) | ABCB1ITGB3ITGA2BALDH1A1FOLH1 | |
| SCHEMBL23879154 | 0.90 | ABCB1 (0.52) | ABCB1ITGB3ITGA2BALDH1A1FOLH1 | |
| SCHEMBL6370564 | 0.89 | ABCB1 (0.51) | ABCB1ITGB3ITGA2BALDH1A1FOLH1 | |
| SCHEMBL29860914 | 0.87 | ABCB1 (0.46) | ABCB1ITGB3ITGA2BALDH1A1FOLH1 | |
| SCHEMBL6370553 | 0.87 | ABCB1 (0.51) | ABCB1ITGB3ITGA2BALDH1A1FOLH1 | |
| SCHEMBL2494968 | 0.87 | ITGB3 (0.59) | ABCB1ITGB3ITGA2BALDH1A1FOLH1 | |
| SCHEMBL31739224 | 0.87 | ITGB3 (0.59) | ABCB1ITGB3ITGA2BALDH1A1FOLH1 | |
| SCHEMBL8067076 | 0.87 | ITGB3 (0.59) | ABCB1ITGB3ITGA2BALDH1A1FOLH1 | |
| SCHEMBL2968658 | 0.87 | ITGB3 (0.59) | ABCB1ITGB3ITGA2BALDH1A1FOLH1 | |
| SCHEMBL21874257 | 0.87 | ABCB1 (0.51) | ABCB1ITGB3ITGA2BALDH1A1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920669-A | Synthesis method of N-methyl-N-benzyloxycarbonyl-L-aspartic acid (4-tert-butyl ester) dicyclohexylamine salt | 吉尔多肽生物制药(大连市)有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-118475590-A | N-alkylamino acid and method for producing peptide containing N-alkylamino acid | 中外制药株式会社 | 2024-08-09 | — | — | CN | disclosed |
| CN-113454058-B | Amino acid having functional group capable of forming intramolecular hydrogen bond, peptide compound containing the amino acid, and process for producing the same | 中外制药株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-117279933-A | Cyclic compounds having selective KRAS inhibition relative to HRAS and NRAS | 中外制药株式会社 | 2023-12-22 | — | — | CN | disclosed |
| CN-114920669-A | Synthesis method of N-methyl-N-benzyloxycarbonyl-L-aspartic acid (4-tert-butyl ester) dicyclohexylamine salt | 吉尔多肽生物制药(大连市)有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114920669-A | Synthesis method of N-methyl-N-benzyloxycarbonyl-L-aspartic acid (4-tert-butyl ester) dicyclohexylamine salt | 吉尔多肽生物制药(大连市)有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114920669-A | Synthesis method of N-methyl-N-benzyloxycarbonyl-L-aspartic acid (4-tert-butyl ester) dicyclohexylamine salt | 吉尔多肽生物制药(大连市)有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114867734-A | Method for synthesizing peptide compound | 中外制药株式会社 | 2022-08-05 | — | — | CN | disclosed |
| US-20040220148-A1 | 5-Membered ring heterocycles as inhibitors of leucocyte adhesion and as VLA-4 antagonists | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-11-04 | — | — | US | disclosed |
| CN-1187490-A | 5-membered ring heterocycles as inhibitors of leucocyte adhesion and as VLA-4 antagonists | HOECHST AG (DE) | 1998-07-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220148-A1 | 5-Membered ring heterocycles as inhibitors of leucocyte adhesion and as VLA-4 antagonists | VCAM1, LTB4R, ITGB4 | ABCB1 433/4885ITGB3 23/4885ITGA2B 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.