Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.64 |
| ▸ | ITGAV | P06756 | 2/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28404391 | 1.00 | ITGB3 (0.64) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL3268531 | 0.88 | ITGB3 (0.65) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7400070 | 0.88 | ITGB3 (0.65) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL6032775 | 0.88 | ITGB3 (0.64) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8713012 | 0.87 | ITGB3 (0.67) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8713009 | 0.87 | ITGB3 (0.67) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL29799532 | 0.86 | ITGB3 (0.52) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7336865 | 0.86 | ITGB3 (0.62) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7622370 | 0.83 | ITGB3 (0.61) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL4067325 | 0.83 | ITGB3 (0.61) | ITGB3ITGA2BITGAVCHRM2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233748-B | Synthesis of tirofiban hydrochloride | 江苏慧聚药业股份有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-111233748-A | Synthesis of tirofiban hydrochloride | 海门慧聚药业有限公司 | 2020-06-05 | — | — | CN | disclosed |