Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.65 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.65 |
| ▸ | ITGAV | P06756 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.45 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400070 | 1.00 | ITGB3 (0.65) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL3273256 | 0.92 | MEN1 (0.56) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL6032775 | 0.89 | ITGB3 (0.64) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8713009 | 0.88 | ITGB3 (0.67) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL28404391 | 0.88 | ITGB3 (0.64) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8713012 | 0.88 | ITGB3 (0.67) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL28404388 | 0.88 | ITGB3 (0.64) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL3266667 | 0.87 | MEN1 (0.60) | ITGB3ITGA2BMEN1KMT2AL3MBTL1 | |
| SCHEMBL7229783 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7279566 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BITGAVCHRM2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384084-A | Method for synthesizing tirofiban hydrochloride | 浙江浙邦制药有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-116041249-A | Preparation method of tirofiban hydrochloride | 辽宁亿帆药业有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-115598257-A | Method for detecting multiple impurities in tirofiban hydrochloride injection | 华夏生生药业（北京）有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-114315697-A | Preparation method of tirofiban hydrochloride | 河北国龙制药有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-111100066-B | Tirofiban hydrochloride intermediate and preparation method of Tirofiban hydrochloride | 石药集团恩必普药业有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-111100066-A | Tirofiban hydrochloride intermediate and preparation method of Tirofiban hydrochloride | 石药集团恩必普药业有限公司 | 2020-05-05 | — | — | CN | claimed |
| CN-117384084-A | Method for synthesizing tirofiban hydrochloride | 浙江浙邦制药有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-116041249-A | Preparation method of tirofiban hydrochloride | 辽宁亿帆药业有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-116041249-A | Preparation method of tirofiban hydrochloride | 辽宁亿帆药业有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-115947680-A | Tirofiban intermediate compound and preparation method thereof | 山东新时代药业有限公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-115598257-A | Method for detecting multiple impurities in tirofiban hydrochloride injection | 华夏生生药业（北京）有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-111233748-B | Synthesis of tirofiban hydrochloride | 江苏慧聚药业股份有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-114315697-A | Preparation method of tirofiban hydrochloride | 河北国龙制药有限公司 | 2022-04-12 | — | — | CN | disclosed |
| EP-0907661-A1 | METHODS AND COMPOSITIONS USEFUL FOR INHIBITION OF alpha v beta 5 MEDIATED ANGIOGENESIS | The Scripps Research Institute (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0844874-A1 | METHODS AND COMPOSITIONS USEFUL FOR INHIBITION OF $g(a) v?$g(b) 5? MEDIATED ANGIOGENESIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-06-03 | — | — | EP | disclosed |
| WO-1997045447-A9 | METHODS AND COMPOSITIONS USEFUL FOR INHIBITION OF αvβ5 MEDIATED ANGIOGENESIS | — | 1998-03-12 | — | — | WO | disclosed |
| WO-1997045137-A1 | METHODS AND COMPOSITIONS USEFUL FOR INHIBITION OF ANGIOGENESIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-12-04 | — | — | WO | disclosed |
| WO-1997045447-A1 | METHODS AND COMPOSITIONS USEFUL FOR INHIBITION OF αvβ5 MEDIATED ANGIOGENESIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-12-04 | — | — | WO | disclosed |
| WO-1997006791-A9 | METHODS AND COMPOSITIONS USEFUL FOR INHIBITION OF αvβ5 MEDIATED ANGIOGENESIS | — | 1997-04-03 | — | — | WO | disclosed |
| WO-1997006791-A1 | METHODS AND COMPOSITIONS USEFUL FOR INHIBITION OF αvβ5 MEDIATED ANGIOGENESIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-02-27 | — | — | WO | disclosed |