Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | KHK | P50053 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28404646 | 0.81 | LMNA (0.45) | MAPTSMN1; SMN2 | |
| SCHEMBL30724194 | 0.73 | GAA (0.76) | RAD52GAAMAPTGFERKDM4E | |
| SCHEMBL3847676 | 0.73 | GAA (0.76) | RAD52GAAMAPTGFERKDM4E | |
| SCHEMBL19732355 | 0.72 | RAD52 (0.48) | RAD52GAAMAPTGFERKDM4E | |
| SCHEMBL2376617 | 0.70 | GAA (0.77) | RAD52GAAMAPTGFERKDM4E | |
| SCHEMBL13548709 | 0.70 | GAA (0.66) | RAD52GAAMAPTGFERKDM4E | |
| SCHEMBL28943250 | 0.70 | CDK4 (0.44) | RAD52GAAMAPTGFERKDM4E | |
| SCHEMBL4950181 | 0.69 | GAA (0.69) | RAD52GAAMAPTGFERKDM4E | |
| SCHEMBL2378263 | 0.68 | GAA (1.00) | RAD52GAAMAPTGFERKDM4E | |
| SCHEMBL6151433 | 0.68 | GAA (1.00) | RAD52GAAMAPTGFERKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278823-B | Heterocyclic compounds as fibroblast growth factor receptor inhibitors | 上海新契博生物科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-111278823-A | Heterocyclic compounds as fibroblast growth factor receptor inhibitors | 上海新契博生物科技有限公司 | 2020-06-12 | — | — | CN | disclosed |