Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28404604 | 0.81 | RAD52 (0.50) | MAPTSMN1; SMN2 | |
| SCHEMBL21761895 | 0.81 | MAPT (0.59) | LMNAOPRM1OPRD1MAPK1L3MBTL1 | |
| SCHEMBL16654009 | 0.77 | TP53 (0.55) | MAPK1L3MBTL1MAPTALDH1A1SIRT6 | |
| SCHEMBL16655629 | 0.75 | MAPT (0.45) | LMNAOPRM1OPRD1MAPK1L3MBTL1 | |
| SCHEMBL2927491 | 0.74 | GAA (0.55) | LMNAOPRM1OPRD1MAPK1L3MBTL1 | |
| SCHEMBL28610614 | 0.73 | LMNA (0.42) | LMNAOPRM1OPRD1MAPK1L3MBTL1 | |
| SCHEMBL13548708 | 0.73 | MAPT (0.74) | MAPK1L3MBTL1MAPTALDH1A1CYP1A2 | |
| SCHEMBL4723486 | 0.73 | L3MBTL1 (0.51) | LMNAOPRM1OPRD1MAPK1L3MBTL1 | |
| SCHEMBL22652221 | 0.73 | L3MBTL1 (0.51) | LMNAOPRM1OPRD1MAPK1L3MBTL1 | |
| SCHEMBL16654429 | 0.73 | GAA (0.61) | LMNAOPRM1OPRD1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278823-B | Heterocyclic compounds as fibroblast growth factor receptor inhibitors | 上海新契博生物科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-111278823-A | Heterocyclic compounds as fibroblast growth factor receptor inhibitors | 上海新契博生物科技有限公司 | 2020-06-12 | — | — | CN | disclosed |