Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27812309 | 0.82 | CTSK (0.48) | CTSKCTSLCTSBSCN9ANPC1 | |
| SCHEMBL15311168 | 0.80 | CTSK (0.49) | CTSKCTSLCTSBSCN9ANPC1 | |
| SCHEMBL27794800 | 0.80 | CTSK (0.49) | CTSKCTSLCTSBSCN9ANPC1 | |
| SCHEMBL14716956 | 0.80 | CTSK (0.49) | CTSKCTSLCTSBSCN9ANPC1 | |
| SCHEMBL28404852 | 0.80 | CTSK (0.45) | CTSKCTSLCTSBSCN9ANPC1 | |
| SCHEMBL28406317 | 0.79 | CTSK (0.44) | CTSKCTSLCTSBSCN9ANPC1 | |
| SCHEMBL29060746 | 0.78 | CTSK (0.47) | CTSKCTSLCTSBSCN9ANPC1 | |
| SCHEMBL28520879 | 0.77 | CTSK (0.52) | CTSKCTSLCTSBSCN9ANPC1 | |
| SCHEMBL28020483 | 0.73 | SCN9A (0.45) | CTSKCTSLCTSBSCN9AADRB2 | |
| SCHEMBL23168379 | 0.73 | ATM (0.61) | CTSKCTSLCTSBATMCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094238-B | Carbamoyl phenylalaninol analogues and uses thereof | 杰资制药爱尔兰有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-111094238-A | Carbamoyl phenylalaninol analogs and uses thereof | 杰资制药爱尔兰有限公司 | 2020-05-01 | — | — | CN | disclosed |