Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13580887 | 0.90 | KMT2A (0.59) | RCE1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL12974482 | 0.83 | ALDH1A1 (0.59) | RCE1MAPK1NR1H4ALDH1A1HDAC1 | |
| SCHEMBL28407865 | 0.81 | KMT2A (0.51) | RCE1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL2361907 | 0.79 | CFTR (0.63) | RCE1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL5512074 | 0.78 | MAPT (0.52) | RCE1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL28503562 | 0.76 | KMT2A (0.50) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL9501204 | 0.74 | TSHR (0.46) | RCE1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL29282563 | 0.74 | RCE1 (0.42) | RCE1KMT2AMEN1NR1H4EPHX2 | |
| SCHEMBL31148968 | 0.74 | RCE1 (0.45) | RCE1KMT2AMAPK1NR1H4ALDH1A1 | |
| SCHEMBL29665053 | 0.74 | MAPT (0.52) | RCE1KMT2AMEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794545-B | Tert-butyl-containing asymmetric α -diimine nickel complex for preparing ultra-high molecular weight polyethylene elastomer, preparation method and application | 中国科学院化学研究所 | 2020-04-21 | — | — | CN | disclosed |