Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8359955 | 0.83 | TDP1 (0.52) | TSHRLMNATYRSMN1; SMN2NPC1 | |
| SCHEMBL23987230 | 0.81 | KIF11 (0.44) | TSHRLMNATYRSMN1; SMN2NPC1 | |
| SCHEMBL14274177 | 0.79 | LMNA (0.44) | TSHRLMNATYRSMN1; SMN2NPC1 | |
| SCHEMBL26005653 | 0.79 | TSHR (0.41) | TSHRLMNATYRSMN1; SMN2NPC1 | |
| SCHEMBL14034732 | 0.78 | KIF11 (0.46) | TSHRLMNATYRSMN1; SMN2NPC1 | |
| SCHEMBL23987222 | 0.78 | KIF11 (0.42) | TSHRLMNATYRSMN1; SMN2NPC1 | |
| SCHEMBL12883526 | 0.77 | TSHR (0.48) | TSHRLMNATYRSMN1; SMN2NPC1 | |
| SCHEMBL11347493 | 0.76 | TSHR (0.72) | TSHRLMNATYRSMN1; SMN2NPC1 | |
| SCHEMBL2392625 | 0.76 | TSHR (0.52) | TSHRLMNATYRSMN1; SMN2NPC1 | |
| SCHEMBL31212783 | 0.76 | TSHR (0.52) | TSHRLMNATYRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317508-B1 | AMINIC ORTHOESTER STABILIZED COMPOSITIONS | CIBA-GEIGY AG (CH) | 1993-06-23 | — | — | EP | claimed |
| EP-0317508-A2 | Aminic orthoester stabilized compositions | CIBA-GEIGY AG (CH) | 1989-05-24 | — | — | EP | claimed |
| EP-0317508-B1 | AMINIC ORTHOESTER STABILIZED COMPOSITIONS | CIBA-GEIGY AG (CH) | 1993-06-23 | — | — | EP | disclosed |
| US-4939300-A | Polymer stabilizer; oxidation, heat, and actinic radiation resistance | CIBA-GEIGY CORPORATION (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0317508-A2 | Aminic orthoester stabilized compositions | CIBA-GEIGY AG (CH) | 1989-05-24 | — | — | EP | disclosed |