Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28405194 | 1.00 | MAPT (0.47) | MAPTCA1CYP1A2HSD17B2SMN1; SMN2 | |
| SCHEMBL28413541 | 0.95 | CA1 (0.47) | MAPTCA1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL28413540 | 0.95 | CA1 (0.47) | MAPTCA1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL14292324 | 0.73 | MAPT (0.68) | MAPTCA1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL27995145 | 0.73 | HSP90AA1 (0.44) | CYP1A2SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL28789732 | 0.73 | MAPT (0.68) | MAPTCA1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL28904165 | 0.73 | GABBR2 (0.38) | MAPTCYP1A2HSD17B2SMN1; SMN2KDM4E | |
| SCHEMBL4543855 | 0.71 | MAPT (0.41) | MAPTCA1ALDH1A1 | |
| SCHEMBL22020695 | 0.70 | CA1 (0.60) | MAPTCA1CYP1A2SMN1; SMN2HPGD | |
| SCHEMBL14292320 | 0.69 | MAPT (0.61) | MAPTCA1SMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111235187-A | Method for preparing β -hydroxyketone by reacting cyclic ketone with aromatic aldehyde under enzyme catalysis | 岭南师范学院 | 2020-06-05 | — | — | CN | disclosed |