Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28810238 | 0.77 | SLC6A2 (0.42) | — | |
| SCHEMBL28413541 | 0.76 | CA1 (0.47) | SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL28413540 | 0.76 | CA1 (0.47) | SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL10723695 | 0.76 | GABBR2 (0.44) | HSP90AA1MAPK1SMN1; SMN2IDO1HDAC3 | |
| SCHEMBL10723686 | 0.76 | GABBR2 (0.44) | HSP90AA1MAPK1SMN1; SMN2IDO1HDAC3 | |
| SCHEMBL28405194 | 0.73 | MAPT (0.47) | SMN1; SMN2KDM4EPOLBRAB9ACYP1A2 | |
| SCHEMBL28405192 | 0.73 | MAPT (0.47) | SMN1; SMN2KDM4EPOLBRAB9ACYP1A2 | |
| SCHEMBL25968608 | 0.73 | SLC6A3 (0.41) | — | |
| SCHEMBL22260289 | 0.73 | SLC6A3 (0.41) | — | |
| SCHEMBL20386529 | 0.73 | IDO1 (0.34) | SMN1; SMN2IDO1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104245663-B | Bicyclic compounds | 东亚荣养株式会社 | 2016-10-26 | — | — | CN | disclosed |
| CN-104245663-A | Bicyclic compounds | TOA EIYO LTD | 2014-12-24 | — | — | CN | disclosed |