SCHEMBL28405306

SCHEMBL28405306

CC(F)(F)C1CN(C(=O)O)C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28404119 0.86 GRM2 (0.32) ATM
SCHEMBL22468569 0.84 CYP2D6 (0.38)
SCHEMBL25313201 0.84 CYP2D6 (0.38)
SCHEMBL25315292 0.84 CYP2D6 (0.38)
SCHEMBL20899956 0.82 ATM (0.31) ATM
SCHEMBL28408901 0.81 RIPK1 (0.35)
SCHEMBL19712361 0.81 CYP2D6 (0.36) ATM
SCHEMBL571772 0.79 CES2 (0.36) ATM
SCHEMBL3077367 0.77 GRM2 (0.36) ATM
SCHEMBL16057933 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111212832-B 1-Benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors 吉利德科学公司 2023-09-15 CN disclosed
CN-111212832-A 1-benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors 吉利德科学公司 2020-05-29 CN disclosed