SCHEMBL28406342

SCHEMBL28406342

Clc1ccc(-c2c[nH]c(Cc3ccncc3)n2)c(Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.40
HSP90AB1 P08238 2/20 0.40
MARS1 P56192 2/20 0.39
CDC7 O00311 2/20 0.38
DBF4 Q9UBU7 2/20 0.38
CCNE1 P24864 2/20 0.37
CDK2 P24941 2/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 2/20 0.36
PIK3CA P42336 1/20 0.36
PIK3CB P42338 1/20 0.36
PIK3CG P48736 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CCNB2 O95067 1/20 0.36
CCNE2 O96020 1/20 0.36
CDK1 P06493 1/20 0.36
CDK4 P11802 1/20 0.36
CCNB1 P14635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2867224 0.90 CXCR2 (0.43) HSP90AA1HSP90AB1LMNAMAPTPIK3CA
SCHEMBL31305442 0.90 CXCR2 (0.43) HSP90AA1HSP90AB1LMNAMAPTPIK3CA
SCHEMBL28399055 0.89 RAB9A (0.40) CCNE1CDK2MAPTMEN1KMT2A
SCHEMBL2860399 0.88 CXCR2 (0.45) HSP90AA1HSP90AB1SMN1; SMN2NPC1RAB9A
SCHEMBL31305406 0.88 CXCR2 (0.45) HSP90AA1HSP90AB1SMN1; SMN2NPC1RAB9A
SCHEMBL26111366 0.86 HSP90AA1 (0.41) HSP90AA1HSP90AB1LMNAMAPTPIK3CA
SCHEMBL1482760 0.85 DHODH (0.40) HSP90AA1HSP90AB1CCNE1CDK2LMNA
SCHEMBL3289934 0.85 CXCR2 (0.40) HSP90AA1HSP90AB1LMNAMAPTPIK3CA
SCHEMBL28398751 0.85 P2RX7 (0.44) MARS1CCNE1CDK2LMNAMAPT
SCHEMBL31305515 0.84 CXCR2 (0.45) HSP90AA1HSP90AB1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111057043-A Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method 深圳市贝加电子材料有限公司 2020-04-24 CN claimed
CN-111057043-B Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method 深圳市贝加电子材料有限公司 2021-11-02 CN disclosed
CN-111057043-A Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method 深圳市贝加电子材料有限公司 2020-04-24 CN disclosed