SCHEMBL28406477

SCHEMBL28406477

COc1ccc(NS(C)(=O)=O)c(Sc2ccc(C)cc2)c1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 7/20 0.56
FFAR4 Q5NUL3 1/20 0.43
ALDH1A1 P00352 6/20 0.42
LMNA P02545 1/20 0.42
PTGS1 P23219 2/20 0.42
MAPT P10636 4/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
TP53 P04637 1/20 0.40
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
MMP12 P39900 1/20 0.40
PTK2 Q05397 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28396015 0.92 PTGS2 (0.59) PTGS2FFAR4ALDH1A1LMNAPTGS1
SCHEMBL28397388 0.86 PTGS2 (0.60) PTGS2ALDH1A1LMNAPTGS1MAPT
SCHEMBL28889111 0.81 PTGS2 (0.55) PTGS2ALDH1A1LMNAPTGS1MAPT
SCHEMBL8092113 0.81 PTGS2 (0.56) PTGS2FFAR4ALDH1A1LMNAPTGS1
SCHEMBL28401357 0.78 PTGS2 (0.52) PTGS2ALDH1A1PTGS1MAPTMEN1
SCHEMBL28399083 0.77 PTGS2 (0.55) PTGS2FFAR4PTGS1GAA
SCHEMBL28393642 0.77 PTGS2 (0.59) PTGS2ALDH1A1PTGS1MAPT
SCHEMBL2760304 0.75 FFAR4 (0.56) PTGS2FFAR4LMNAPTGS1GAA
SCHEMBL8736422 0.75 ACHE (0.48) ALDH1A1LMNAMAPTMEN1KMT2A
SCHEMBL30293256 0.75 FFAR4 (0.56) PTGS2FFAR4LMNAPTGS1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111170914-B Selenium/sulfuryl sulfonyl arylamine compound and selenium/sulfuration method thereof 成都大学 2021-12-21 CN disclosed
CN-111170914-A Selenium/sulfuryl sulfonyl arylamine compound and selenium/sulfuration method thereof 成都大学 2020-05-19 CN disclosed