Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470535 | 1.00 | DNMT1 (0.44) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL14964628 | 0.72 | ALDH1A1 (0.42) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL1818501 | 0.72 | KDM4E (0.41) | DNMT1ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL2961439 | 0.71 | MCL1 (0.45) | ALDH1A1HSD17B10TSHRTDP1MAPT | |
| SCHEMBL24062 | 0.69 | MEN1 (0.37) | DNMT1ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL2963169 | 0.69 | MCL1 (0.47) | ALDH1A1HSD17B10TSHRTDP1MAPT | |
| SCHEMBL14777719 | 0.68 | DNMT1 (0.64) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| Phenanthrene SCHEMBL4879064 | 0.67 | ALDH1A1 (0.80) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL5047700 | 0.67 | DNMT1 (0.69) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL31045609 | 0.67 | DNMT1 (0.69) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111206262-B | Synthesis method of N-phosphino-substituted carbazole and indole derivatives | 新疆大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-111206262-A | Synthesis method of N-phosphino-substituted carbazole and indole derivatives | 新疆大学 | 2020-05-29 | — | — | CN | disclosed |