Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL30910408 | 1.00 | LMNA (0.56) | LMNAAKT1TGM2ALDH1A1KDM4E | |
| Anthraquinone SCHEMBL9320065 | 0.87 | MEN1 (0.57) | LMNAAKT1ALDH1A1KDM4EMAPT | |
| Acrylic Acid SCHEMBL29733337 | 0.87 | BCAT2 (0.44) | LMNAAKT1TGM2ALDH1A1MAPT | |
| Naphthalene SCHEMBL30742789 | 0.86 | LMNA (0.59) | LMNAAKT1TGM2ALDH1A1KDM4E | |
| Naphthalene SCHEMBL30721503 | 0.86 | LMNA (0.59) | LMNAAKT1TGM2ALDH1A1KDM4E | |
| Naphthalene SCHEMBL3296369 | 0.86 | LMNA (0.59) | LMNAAKT1TGM2ALDH1A1KDM4E | |
| Phthalic Anhydride SCHEMBL27347577 | 0.84 | TDP1 (0.61) | LMNAAKT1TGM2ALDH1A1KDM4E | |
| Biphenyl SCHEMBL36309 | 0.83 | LMNA (0.56) | LMNAAKT1TGM2ALDH1A1KDM4E | |
| Acrylic Acid SCHEMBL28406645 | 0.83 | LMNA (0.56) | LMNAAKT1TGM2ALDH1A1KDM4E | |
| Triphenylene SCHEMBL29117898 | 0.83 | LMNA (0.56) | LMNAAKT1TGM2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108276376-B | Novel diphenylpropenes derivative, preparation method thereof and pharmaceutical composition | 北京理工大学 | 2020-06-05 | — | — | CN | disclosed |