Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28406808 | 0.92 | KMT2A (0.44) | KMT2AMAOAMAOBGRIA4 | |
| SCHEMBL28890242 | 0.85 | MAPT (0.45) | KMT2AFNTAFNTB | |
| SCHEMBL28411193 | 0.85 | MAPT (0.44) | KMT2AHTTMEN1 | |
| SCHEMBL15172938 | 0.65 | HTT (0.48) | KMT2AFNTAFNTBHTTMEN1 | |
| SCHEMBL5737978 | 0.65 | KMT2A (0.63) | KMT2AHTTMEN1TSHR | |
| SCHEMBL9097606 | 0.65 | BACE1 (0.39) | KMT2AMAOBMEN1 | |
| SCHEMBL9042171 | 0.62 | PDE9A (0.41) | KMT2AMAOAMAOBHTTMEN1 | |
| SCHEMBL8721290 | 0.62 | FASN (0.41) | KMT2AMAOAMAOBMEN1 | |
| SCHEMBL15496856 | 0.61 | LMNA (0.70) | KMT2AMEN1 | |
| SCHEMBL13445258 | 0.61 | LMNA (0.70) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217812-A | Process for preparing 2-bromoindolizine derivatives | 淮阴师范学院 | 2020-06-02 | — | — | CN | disclosed |