Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28406808 | 0.92 | KMT2A (0.44) | KMT2A | |
| SCHEMBL28411193 | 0.87 | MAPT (0.44) | MAPTNPSR1KMT2A | |
| SCHEMBL28407126 | 0.85 | KMT2A (0.40) | KMT2AFNTAFNTB | |
| SCHEMBL9097606 | 0.65 | BACE1 (0.39) | MAPTNPSR1KMT2A | |
| SCHEMBL8721290 | 0.64 | FASN (0.41) | MAPTKMT2A | |
| SCHEMBL11445310 | 0.64 | VNN1 (0.61) | L3MBTL1 | |
| SCHEMBL9694596 | 0.62 | TSHR (0.59) | MAPTKMT2A | |
| SCHEMBL9022977 | 0.62 | CCR2 (0.43) | MAPTPOLBNPSR1KMT2ACYP1A2 | |
| SCHEMBL27211489 | 0.61 | MAPT (0.44) | MAPTPOLBNPSR1KMT2ACYP1A2 | |
| SCHEMBL10874927 | 0.61 | SRD5A2 (0.65) | MAPTPOLBKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217812-A | Process for preparing 2-bromoindolizine derivatives | 淮阴师范学院 | 2020-06-02 | — | — | CN | disclosed |