Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2932043 | 0.98 | KMT2A (0.41) | KMT2AALDH1A1POLBADORA2AADORA2B | |
| Iodide SCHEMBL28890293 | 0.85 | KMT2A (0.42) | KMT2AALDH1A1POLBCYP3A4CYP1A2 | |
| SCHEMBL18250734 | 0.82 | KMT2A (0.43) | KMT2AALDH1A1POLBCYP3A4CYP1A2 | |
| SCHEMBL9460005 | 0.80 | KMT2A (0.36) | KMT2AALDH1A1POLBCYP3A4CYP1A2 | |
| SCHEMBL9460390 | 0.80 | KMT2A (0.36) | KMT2AALDH1A1POLBCYP3A4CYP1A2 | |
| SCHEMBL2793745 | 0.80 | KMT2A (0.36) | KMT2AALDH1A1POLBCYP3A4CYP1A2 | |
| SCHEMBL18250723 | 0.79 | ALDH1A1 (0.49) | KMT2AALDH1A1POLBCYP3A4CYP1A2 | |
| SCHEMBL18250722 | 0.79 | ALDH1A1 (0.42) | KMT2AALDH1A1POLBCYP3A4CYP1A2 | |
| Iodide SCHEMBL5531813 | 0.79 | ALDH1A1 (0.36) | KMT2AALDH1A1POLBCYP3A4CYP1A2 | |
| SCHEMBL23570500 | 0.78 | KMT2A (0.39) | KMT2AALDH1A1POLBCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108538606-B | Solid electrolyte of dye-sensitized solar cell and preparation method thereof | 西安智财全技术转移中心有限公司 | 2020-06-16 | — | — | CN | disclosed |