Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18250734 | 0.98 | KMT2A (0.43) | KMT2AALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL18250723 | 0.87 | ALDH1A1 (0.49) | KMT2AALDH1A1POLBCYP1A2CYP3A4 | |
| Iodide SCHEMBL28407463 | 0.85 | KMT2A (0.40) | KMT2AALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL2932043 | 0.82 | KMT2A (0.41) | KMT2AALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL23168834 | 0.78 | TLR8 (0.43) | KMT2AALDH1A1POLBBRD4SLC2A1 | |
| SCHEMBL18250730 | 0.78 | ALDH1A1 (0.42) | KMT2AALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL27543828 | 0.78 | SLC2A1 (0.34) | KMT2AALDH1A1POLBBRD4SLC2A1 | |
| SCHEMBL11009083 | 0.78 | ALDH1A1 (0.42) | KMT2AALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL18250275 | 0.78 | SMN1; SMN2 (0.38) | KMT2AALDH1A1POLBBRD4SLC2A1 | |
| SCHEMBL9460005 | 0.77 | KMT2A (0.36) | KMT2AALDH1A1POLBCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108538606-B | Solid electrolyte of dye-sensitized solar cell and preparation method thereof | 西安智财全技术转移中心有限公司 | 2020-06-16 | — | — | CN | disclosed |