Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20540427 | 0.84 | CCNC (0.37) | MAPKAPK2HDAC1CCNCCDK8NTRK1 | |
| SCHEMBL28405367 | 0.79 | LMNA (0.35) | NTRK1CA12CA1CA2CA9 | |
| SCHEMBL16118399 | 0.79 | CCNC (0.40) | IDO1CCNCCDK8NTRK1MAPK14 | |
| SCHEMBL28755600 | 0.78 | NTRK1 (0.39) | NTRK1CYP1A2CYP3A4GAACYP2D6 | |
| SCHEMBL21164202 | 0.76 | GSK3B (0.37) | IDO1MAPK14NAMPTGSK3BDYRK1A | |
| SCHEMBL5493771 | 0.75 | CCNC (0.41) | IDO1MAPKAPK2CCNCCDK8NTRK1 | |
| SCHEMBL5497817 | 0.73 | CCNC (0.46) | MAPKAPK2CCNCCDK8CA12CA1 | |
| SCHEMBL5492718 | 0.72 | BCHE (0.40) | IDO1CCNCCDK8NTRK1NAMPT | |
| SCHEMBL16638612 | 0.72 | IDO1 (0.43) | IDO1HDAC1NTRK1CA12CA1 | |
| SCHEMBL5499689 | 0.72 | CA12 (0.38) | IDO1CCNCCDK8CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107787324-B | Process for preparing carbamoylaminopyrazole derivatives | 桑多斯股份公司 | 2020-05-19 | — | — | CN | disclosed |