Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPER1 | Q99527 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28407659 | 1.00 | BRD4 (0.37) | BRD4CREBBPEP300KCNH2MEN1 | |
| SCHEMBL30557222 | 0.86 | BRD4 (0.35) | BRD4CREBBPEP300MEN1KMT2A | |
| SCHEMBL21112969 | 0.84 | CREBBP (0.36) | BRD4CREBBPEP300MEN1CYP1A2 | |
| SCHEMBL21112970 | 0.84 | CREBBP (0.36) | BRD4CREBBPEP300MEN1CYP1A2 | |
| SCHEMBL21112675 | 0.80 | EP300 (0.33) | BRD4CREBBPEP300MEN1CYP1A2 | |
| SCHEMBL21112672 | 0.80 | EP300 (0.33) | BRD4CREBBPEP300MEN1CYP1A2 | |
| SCHEMBL21112156 | 0.74 | MGLL (0.37) | BRD4CREBBPEP300MEN1KMT2A | |
| SCHEMBL21112155 | 0.74 | MGLL (0.37) | BRD4CREBBPEP300MEN1KMT2A | |
| SCHEMBL28403736 | 0.74 | MKNK1 (0.35) | BRD4CREBBPEP300MEN1KMT2A | |
| SCHEMBL28403738 | 0.74 | MKNK1 (0.35) | BRD4CREBBPEP300MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212832-A | 1-benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2020-05-29 | — | — | CN | disclosed |