Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28345840 | 0.88 | CAMK2A (0.33) | KMT2AMEN1POLBPLA2G1BGAPDH | |
| SCHEMBL27989099 | 0.83 | KMT2A (0.37) | KMT2AMEN1POLBGAPDHHSPA1A | |
| SCHEMBL3911490 | 0.83 | KMT2A (0.48) | KMT2AMEN1POLBPLA2G1BGAPDH | |
| SCHEMBL28231557 | 0.81 | HSD17B10 (0.30) | — | |
| SCHEMBL28061624 | 0.79 | — | — | |
| SCHEMBL28408789 | 0.78 | — | — | |
| SCHEMBL28288836 | 0.78 | CHRNB2 (0.40) | KMT2AMEN1CA1CA2HTR2A | |
| SCHEMBL27362318 | 0.78 | KCNH2 (0.42) | HSPA1APTPN7TDP1EGFR | |
| SCHEMBL27714387 | 0.77 | CHRNB4 (0.43) | GAPDHHSPA1APTPN7ERN1 | |
| SCHEMBL28127795 | 0.77 | KDM1A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072546-B | Synthesis method of 5-ethynylindoline-2, 3-diketone | 阿里生物新材料（常州）有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-111072546-A | Synthesis method of 5-ethynylindoline-2, 3-diketone | 阿里生物新材料（常州）有限公司 | 2020-04-28 | — | — | CN | claimed |
| CN-111072546-B | Synthesis method of 5-ethynylindoline-2, 3-diketone | 阿里生物新材料（常州）有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-111072546-B | Synthesis method of 5-ethynylindoline-2, 3-diketone | 阿里生物新材料（常州）有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-111072546-A | Synthesis method of 5-ethynylindoline-2, 3-diketone | 阿里生物新材料（常州）有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-111072546-A | Synthesis method of 5-ethynylindoline-2, 3-diketone | 阿里生物新材料（常州）有限公司 | 2020-04-28 | — | — | CN | disclosed |