SCHEMBL28409010

SCHEMBL28409010

CC(C)c1ccc(N=Nc2ccc(O)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
ESR1 P03372 1/20 0.52
PDCD1 Q15116 1/20 0.52
ESR2 Q92731 1/20 0.52
CD274 Q9NZQ7 1/20 0.52
GLB1 P16278 1/20 0.52
CTRB1 P17538 1/20 0.52
CTRC Q99895 1/20 0.52
RAB9A P51151 3/20 0.51
HSP90AA1 P07900 1/20 0.48
CYP2C9 P11712 1/20 0.47
MAPT P10636 3/20 0.46
LMNA P02545 1/20 0.46
HPGD P15428 1/20 0.46
NFKB1 P19838 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
EGFR P00533 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28409009 1.00 NPC1 (0.54) NPC1MEN1KMT2AESR1PDCD1
SCHEMBL20251140 0.88 RAB9A (0.50) NPC1MEN1KMT2ARAB9ACYP2C9
SCHEMBL20251135 0.88 RAB9A (0.50) NPC1MEN1KMT2ARAB9ACYP2C9
SCHEMBL28954 0.85 ESR1 (0.68) NPC1MEN1KMT2AESR1PDCD1
Hydroquinone SCHEMBL9580215 0.85 ESR1 (0.68) NPC1MEN1KMT2AESR1PDCD1
SCHEMBL22328174 0.85 NPC1 (0.48) NPC1MEN1KMT2AESR1PDCD1
SCHEMBL28800543 0.83 ESR1 (0.65) NPC1MEN1KMT2AESR1PDCD1
SCHEMBL28657617 0.83 ESR1 (0.65) NPC1MEN1KMT2AESR1PDCD1
SCHEMBL29133983 0.83 ESR1 (0.65) NPC1MEN1KMT2AESR1PDCD1
SCHEMBL30171502 0.83 ESR1 (0.65) NPC1MEN1KMT2AESR1PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111233697-A Acrylate azobenzene capable of solid-liquid conversion and preparation method thereof 桂林理工大学 2020-06-05 CN disclosed