Propionic Acid

Propionic Acid

SCHEMBL28409072

CCC(=O)O.Cc1c(C(=O)O)cc(O)c(O)c1O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGB1 P09429 1/20 0.41
CXCL12 P48061 1/20 0.41
CSNK2A1 P68400 1/20 0.40
SELP P16109 3/20 0.39
SELL P14151 2/20 0.39
KDM4E B2RXH2 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
BCL2 P10415 1/20 0.39
MCL1 Q07820 1/20 0.39
THRB P10828 1/20 0.38
CA12 O43570 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
CA3 P07451 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39512 0.90 CSNK2A1 (0.47) HMGB1CXCL12CSNK2A1SELPSELL
Water SCHEMBL28507409 0.88 CSNK2A1 (0.45) HMGB1CXCL12CSNK2A1SELPSELL
Hydrogen Sulfide SCHEMBL27850210 0.86 CSNK2A1 (0.44) HMGB1CXCL12CSNK2A1SELPSELL
SCHEMBL2456581 0.78 CSNK2A1 (0.47) HMGB1CXCL12CSNK2A1SELPSELL
Gallic Acid Methyl Ester SCHEMBL2573657 0.75 LMNA (0.66) SELPSELLKDM4ETDP1MEN1
SCHEMBL27534718 0.75 LDHA (0.44) HMGB1CXCL12CSNK2A1SELPSELL
SCHEMBL28927809 0.74 CA12 (0.54) TDP1CA12CA1CA2CA7
SCHEMBL3761832 0.74 HMGB1 (0.52) HMGB1CXCL12CSNK2A1KDM4ETDP1
SCHEMBL23756593 0.73 CSNK2A1 (0.42) HMGB1CXCL12CSNK2A1SELPSELL
SCHEMBL39598 0.73 SELL (0.42) HMGB1CXCL12CSNK2A1SELPSELL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111289635-A Method for measuring content of index components in bile and separating and identifying 30 chemical components after oral administration of phyllanthus emblica tannin parts 北京中医药大学 2020-06-16 CN disclosed