Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29441687 | 0.88 | SLC6A3 (0.61) | GAASLC6A3SLC6A4SLC6A2MAPT | |
| SCHEMBL3920552 | 0.88 | SLC6A3 (0.61) | GAASLC6A3SLC6A4SLC6A2MAPT | |
| SCHEMBL4827474 | 0.83 | HNF4A (0.66) | GAASLC6A3SLC6A4SLC6A2MAPT | |
| SCHEMBL28414807 | 0.82 | SLC6A3 (0.52) | GAASLC6A3SLC6A4SLC6A2MAPT | |
| SCHEMBL6852742 | 0.81 | HNF4A (0.69) | GAAMAPTALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28414121 | 0.80 | HNF4A (0.67) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6434822 | 0.78 | MAPT (0.54) | GAASLC6A3SLC6A4SLC6A2MAPT | |
| SCHEMBL6438400 | 0.77 | GAA (0.54) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3133724 | 0.77 | CHEK1 (0.52) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2897002 | 0.76 | GAA (0.56) | GAASLC6A3SLC6A4SLC6A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101845-B | Preparation method of eltrombopag | 苏州科伦药物研究有限公司 | 2020-05-15 | — | — | CN | disclosed |