Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.43 |
| ▸ | ITGAL | P20701 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485100 | 0.84 | KMT2A (0.62) | SMN1; SMN2KDM4EMAPTMEN1POLB | |
| SCHEMBL7485105 | 0.84 | KMT2A (0.62) | SMN1; SMN2KDM4EMAPTMEN1POLB | |
| SCHEMBL18029238 | 0.84 | KMT2A (0.62) | SMN1; SMN2KDM4EMAPTMEN1POLB | |
| SCHEMBL28409195 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EMAPTMEN1POLB | |
| SCHEMBL24328360 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EMAPTMEN1POLB | |
| SCHEMBL24328926 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EMAPTMEN1POLB | |
| SCHEMBL24328922 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EMAPTMEN1POLB | |
| SCHEMBL23226236 | 0.81 | ITGB2 (0.43) | SMN1; SMN2KDM4EMAPTMEN1POLB | |
| SCHEMBL24328929 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4EMAPTMEN1POLB | |
| SCHEMBL24328917 | 0.80 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EMAPTMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303001-B | Synthesis method of indole mono-substituted 2-hydroxy-3- (1H-indol-3-yl) propionic acid compound | 苏州爱玛特生物科技有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-111303001-A | Synthesis method of indole mono-substituted 2-hydroxy-3- (1H-indol-3-yl) propionic acid compound | 苏州爱玛特生物科技有限公司 | 2020-06-19 | — | — | CN | disclosed |