Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485105 | 1.00 | KMT2A (0.62) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL18029238 | 1.00 | KMT2A (0.62) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL458570 | 0.84 | KMT2A (0.63) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL30356567 | 0.84 | KMT2A (0.63) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL27917618 | 0.84 | KMT2A (0.63) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL7480435 | 0.84 | KMT2A (0.63) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL30084863 | 0.84 | KMT2A (0.68) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL28409192 | 0.84 | SMN1; SMN2 (0.61) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL1114867 | 0.84 | KMT2A (0.68) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL18029267 | 0.84 | KMT2A (0.68) | KMT2AKDM4EMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200247858-A1 | AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-08-06 | — | — | US | claimed |
| EP-3678683-A2 | AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF | Fog Pharmaceuticals, Inc. (US) | 2020-07-15 | — | — | EP | claimed |
| CN-111372942-A | β -catenin function modulating agents and methods thereof | 弗格制药有限公司 | 2020-07-03 | — | — | CN | claimed |
| WO-2019051327-A2 | AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2019-03-14 | — | — | WO | claimed |
| EP-1219603-A2 | Tryptophan analogs in proteins, peptides and peptidic structures | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2002-07-03 | — | — | EP | claimed |
| US-20250354108-A1 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | UNIV DANMARKS TEKNISKE (DK) | 2025-11-20 | — | — | US | disclosed |
| EP-4526426-A2 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | Danmarks Tekniske Universitet (DK) | 2025-03-26 | — | — | EP | disclosed |
| EP-3596089-B1 | ANTIBACTERIAL COMPOUNDS | UNIV NOTTINGHAM (GB) | 2023-12-06 | — | — | EP | disclosed |
| US-11834482-B2 | Agents modulating beta-catenin functions and methods thereof | FOG PHARMACEUTICALS, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| WO-2023222879-A2 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | DANMARKS TEKNISKE UNIVERSITET (DK) | 2023-11-23 | — | — | WO | disclosed |
| US-20230357744-A1 | ENGINEERED TRYPTOPHAN DECARBOXYLASES AND USES THEREOF FOR SYNTHESIZING TRYPTAMINE ANALOGS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2023-11-09 | — | — | US | disclosed |
| US-20220290196-A1 | GENETICALLY ENGINEERED MICROBES AND BIOSYNTHETIC METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-09-15 | — | — | US | disclosed |
| US-10752927-B2 | Method for the synthesis of tryptophan analogs in aqueous solvents at reduced temperatures | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-08-25 | — | — | US | disclosed |
| US-20200247858-A1 | AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-08-06 | — | — | US | disclosed |
| EP-3678683-A2 | AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF | Fog Pharmaceuticals, Inc. (US) | 2020-07-15 | — | — | EP | disclosed |
| CN-111372942-A | β -catenin function modulating agents and methods thereof | 弗格制药有限公司 | 2020-07-03 | — | — | CN | disclosed |
| US-20200199118-A1 | ANTIBACTERIAL COMPOUNDS | THE UNIVERSITY OF NOTTINGHAM (GB) | 2020-06-25 | — | — | US | disclosed |
| US-20190271016-A1 | METHOD FOR THE SYNTHESIS OF TRYPTOPHAN ANALOGS IN AQUEOUS SOLVENTS AT REDUCED TEMPERATURES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-09-05 | — | — | US | disclosed |
| WO-2019051327-A2 | AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2019-03-14 | — | — | WO | disclosed |
| EP-1219603-A2 | Tryptophan analogs in proteins, peptides and peptidic structures | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2002-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199118-A1 | ANTIBACTERIAL COMPOUNDS | CFTR, CLPP, MRPL21 | KMT2A 4669/4885KDM4E 4470/4885MAPT 3616/4885 |
| US-20200247858-A1 | AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF | CTNNB1, CTNNBL1, CTNNA1 | KMT2A 3036/4885KDM4E 1902/4885MAPT 3674/4885 |
| US-20250354108-A1 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | INMT, KARS1, MIA3 | KMT2A 445/4885KDM4E 2243/4885MAPT 3008/4885 |
| US-11834482-B2 | Agents modulating beta-catenin functions and methods thereof | CTNNB1, CTNNBL1, CTNNA1 | KMT2A 3036/4885KDM4E 1902/4885MAPT 3674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.