Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.47 |
| ▸ | ITGAL | P20701 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28409195 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2GPR84ADRB3ITGB2ICAM1 | |
| SCHEMBL29406297 | 0.84 | KMT2A (0.62) | GPR84ADRB3ITGB2ICAM1ITGAL | |
| SCHEMBL109838 | 0.84 | KMT2A (0.62) | GPR84ADRB3ITGB2ICAM1ITGAL | |
| SCHEMBL21055747 | 0.84 | KMT2A (0.62) | GPR84ADRB3ITGB2ICAM1ITGAL | |
| SCHEMBL29556951 | 0.84 | KMT2A (0.62) | GPR84ADRB3ITGB2ICAM1ITGAL | |
| SCHEMBL109837 | 0.84 | KMT2A (0.62) | GPR84ADRB3ITGB2ICAM1ITGAL | |
| SCHEMBL18028997 | 0.84 | KMT2A (0.62) | GPR84ADRB3ITGB2ICAM1ITGAL | |
| SCHEMBL24328896 | 0.83 | GPR84 (0.55) | SMN1; SMN2GPR84ADRB3ITGB2ICAM1 | |
| SCHEMBL24328926 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2GPR84ADRB3ITGB2ICAM1 | |
| SCHEMBL24328922 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2GPR84ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| WO-2022078416-A1 | NOVEL GLUTAMINE ANALOGS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | GLUL, GATD3, GLS | SMN1; SMN2 3812/4885GPR84 178/4885ADRB3 4700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.