Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.60 |
| ▸ | TNF | P01375 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.52 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682291 | 0.87 | ADORA2B (0.62) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL9392791 | 0.81 | ADORA2B (0.58) | ADORA2BTNFUSP2LMNACYP1A2 | |
| Bisdionin C SCHEMBL10018600 | 0.79 | CHIT1 (0.75) | ADORA2BTNFUSP2LMNACYP1A2 | |
| Bisdionin D SCHEMBL16120988 | 0.79 | ADORA2B (0.79) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL8071917 | 0.79 | ADORA2B (0.60) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL11301985 | 0.79 | ADORA2B (0.79) | ADORA2BTNFUSP2LMNACYP1A2 | |
| 1-[4-Carboxypropyl]-3,7-Dimethylxanthine SCHEMBL5420399 | 0.78 | ADORA2B (0.74) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL17682292 | 0.78 | ADORA2B (0.62) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL16120981 | 0.78 | ADORA2B (0.77) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL5412111 | 0.77 | ADORA2B (0.81) | ADORA2BTNFUSP2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233863-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-108348525-B | Medical application of hydroxyl purine compound | 广东众生睿创生物科技有限公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-111233863-A | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-105566324-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2020-04-03 | — | — | CN | disclosed |