Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28414821 | 0.85 | LMNA (0.53) | LMNAMAPTL3MBTL1SGMS2LRRK2 | |
| SCHEMBL28417425 | 0.85 | LRRK2 (0.72) | SGMS2LRRK2KMT2A | |
| SCHEMBL30779518 | 0.85 | LMNA (0.55) | LMNAMAPTL3MBTL1SGMS2LRRK2 | |
| SCHEMBL21644520 | 0.85 | LMNA (0.55) | LMNAMAPTL3MBTL1SGMS2LRRK2 | |
| SCHEMBL28419055 | 0.81 | SGMS2 (0.59) | LMNAMAPTL3MBTL1SGMS2LRRK2 | |
| SCHEMBL29244975 | 0.81 | SGMS2 (0.54) | LMNAMAPTL3MBTL1SGMS2ALDH1A1 | |
| SCHEMBL28415323 | 0.79 | NPC1 (0.54) | L3MBTL1SGMS2LRRK2SMN1; SMN2KMT2A | |
| SCHEMBL382849 | 0.78 | FOLH1 (0.62) | MAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21678110 | 0.76 | LMNA (0.68) | LMNAMAPTL3MBTL1SGMS2ALDH1A1 | |
| SCHEMBL1648346 | 0.75 | HTT (0.50) | L3MBTL1ALDH1A1MAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111164074-B | Heat shock protein 90 inhibitors | 台北医学大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-111164074-A | Heat shock protein 90 inhibitor | 台北医学大学 | 2020-05-15 | — | — | CN | disclosed |