Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28409582 | 1.00 | ALDH1A1 (0.63) | ALDH1A1HPGDDRD2DRD3KMT2A | |
| SCHEMBL28414245 | 0.88 | ALDH1A1 (0.65) | ALDH1A1HPGDDRD2DRD3KMT2A | |
| SCHEMBL28407968 | 0.88 | ALDH1A1 (0.65) | ALDH1A1HPGDDRD2DRD3KMT2A | |
| SCHEMBL28403859 | 0.86 | ALDH1A1 (0.63) | ALDH1A1HPGDDRD2DRD3KMT2A | |
| SCHEMBL28407785 | 0.86 | ALDH1A1 (0.63) | ALDH1A1HPGDDRD2DRD3KMT2A | |
| SCHEMBL28407787 | 0.86 | ALDH1A1 (0.63) | ALDH1A1HPGDDRD2DRD3KMT2A | |
| SCHEMBL28403858 | 0.86 | ALDH1A1 (0.63) | ALDH1A1HPGDDRD2DRD3KMT2A | |
| SCHEMBL4167189 | 0.85 | ALDH1A1 (0.84) | ALDH1A1HPGDKMT2ANPC1KDM4E | |
| SCHEMBL28409709 | 0.81 | ALDH1A1 (0.63) | ALDH1A1HPGDDRD2DRD3KMT2A | |
| SCHEMBL28409708 | 0.81 | ALDH1A1 (0.63) | ALDH1A1HPGDDRD2DRD3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269203-A | N-cyclohexyl-furan-2-formamide compound and preparation method and application thereof | 上海中泽医药科技有限公司 | 2020-06-12 | — | — | CN | disclosed |