Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.84 |
| ▸ | HPGD | P15428 | 1/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206231 | 0.92 | ALDH1A1 (0.72) | ALDH1A1HPGDKMT2ANPC1LMNA | |
| SCHEMBL14934861 | 0.92 | ALDH1A1 (0.72) | ALDH1A1HPGDKMT2ANPC1LMNA | |
| SCHEMBL6206225 | 0.92 | ALDH1A1 (0.72) | ALDH1A1HPGDKMT2ANPC1LMNA | |
| SCHEMBL8062381 | 0.91 | ALDH1A1 (1.00) | ALDH1A1HPGDNPC1TSHRNPSR1 | |
| SCHEMBL1844542 | 0.89 | ALDH1A1 (0.72) | ALDH1A1HPGDKMT2ANPC1TSHR | |
| SCHEMBL28404651 | 0.89 | ALDH1A1 (0.72) | ALDH1A1HPGDKMT2ANPC1TSHR | |
| SCHEMBL28407968 | 0.87 | ALDH1A1 (0.65) | ALDH1A1HPGDKMT2ANPC1KDM4E | |
| SCHEMBL28414245 | 0.87 | ALDH1A1 (0.65) | ALDH1A1HPGDKMT2ANPC1KDM4E | |
| SCHEMBL28409709 | 0.85 | ALDH1A1 (0.63) | ALDH1A1HPGDKMT2ANPC1LMNA | |
| SCHEMBL28409708 | 0.85 | ALDH1A1 (0.63) | ALDH1A1HPGDKMT2ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710287-B | Ring-opening boronation reaction method for cyclopropane compound under no metal catalysis | 中国科学院兰州化学物理研究所 | 2024-01-09 | — | — | CN | disclosed |
| CN-115710287-A | Ring-opening boronization reaction method of cyclopropane compound under condition of no metal catalysis | 中国科学院兰州化学物理研究所 | 2023-02-24 | — | — | CN | disclosed |
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRUENENTHAL GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
| CN-1136198-C | Novel benzyl pyrimidines | ��������ҩ�ɷ�����˾ | 2004-01-28 | — | — | CN | disclosed |
| EP-0793656-B1 | NOVEL BENZYL PYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2003-03-26 | — | — | EP | disclosed |
| US-5763450-A | BACTERICIDES; TREATMENT OF INFECTIOUS DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| CN-1166831-A | Novel benzyl pyrimidines | HOFFMANN LA ROCHE (CH) | 1997-12-03 | — | — | CN | disclosed |
| EP-0793656-A1 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996016046-A2 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRM1, GRIN1, GRM2 | ALDH1A1 2269/4885HPGD 2246/4885KMT2A 1642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.