Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28407552 | 0.85 | — | — | |
| SCHEMBL15765124 | 0.71 | RXFP1 (0.43) | RXFP1KDM4EALDH1A1HPGD | |
| SCHEMBL28412403 | 0.67 | RXFP1 (0.40) | RXFP1KDM4EALDH1A1HPGD | |
| SCHEMBL4226441 | 0.65 | RXFP1 (0.43) | RXFP1KDM4EALDH1A1HPGD | |
| SCHEMBL28416923 | 0.62 | RAB9A (0.39) | RXFP1KDM4EALDH1A1HPGD | |
| SCHEMBL4229876 | 0.62 | KDM4E (0.41) | RXFP1KDM4EALDH1A1HPGD | |
| SCHEMBL28409533 | 0.61 | RXFP1 (0.38) | RXFP1KDM4EALDH1A1HPGD | |
| SCHEMBL31634103 | 0.60 | RXFP1 (0.30) | RXFP1 | |
| SCHEMBL19733991 | 0.60 | MAOA (0.34) | RXFP1KDM4EALDH1A1HPGD | |
| SCHEMBL17974430 | 0.60 | MAOA (0.36) | RXFP1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116577-A | Fused tetracyclic compounds and application thereof in medicines | 广东东阳光药业有限公司 | 2020-05-08 | — | — | CN | disclosed |