SCHEMBL28410141

SCHEMBL28410141

Cc1ccc(C(=O)c2ccccc2C(=O)c2ccccc2)c(C)c1C

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.55
ALDH1A1 P00352 3/20 0.51
NPSR1 Q6W5P4 1/20 0.50
POLB P06746 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
MYC P01106 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
KMT2A Q03164 1/20 0.45
CDC25B P30305 2/20 0.44
CDC25A P30304 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
NR4A1 P22736 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30007458 0.94 ALDH1A1 (0.50) AKR1C3ALDH1A1NPSR1GAAMAPT
SCHEMBL109891 0.94 ALDH1A1 (0.50) AKR1C3ALDH1A1NPSR1GAAMAPT
SCHEMBL28684235 0.91 ALDH1A1 (0.49) AKR1C3ALDH1A1NPSR1POLBGAA
SCHEMBL28432848 0.91 ALDH1A1 (0.52) AKR1C3ALDH1A1NPSR1GAAMAPT
SCHEMBL28648761 0.88 AKR1C3 (0.44) AKR1C3ALDH1A1NPSR1GAAMAPT
SCHEMBL10007412 0.87 ALDH1A1 (0.59) AKR1C3ALDH1A1NPSR1POLBGAA
SCHEMBL26194148 0.86 ATM (0.60) ALDH1A1NPSR1POLBGAAMAPT
SCHEMBL26194147 0.85 ALDH1A1 (0.51) ALDH1A1POLBMAPTKMT2AATM
SCHEMBL6465028 0.84 CDC25B (0.56) AKR1C3ALDH1A1POLBMAPTKMT2A
SCHEMBL287915 0.83 AKR1C3 (0.55) AKR1C3ALDH1A1NPSR1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111278879-A Curable compositions based on immiscible reactive components and block copolymers 阿科玛法国公司 2020-06-12 CN disclosed