SCHEMBL6465028

SCHEMBL6465028

Cc1ccc(C(=O)c2ccc(-c3ccccc3)cc2)c(C)c1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.56
ATM Q13315 1/20 0.56
MAPT P10636 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
ALDH1A1 P00352 2/20 0.46
AKR1C3 P42330 1/20 0.46
RAB9A P51151 4/20 0.46
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
KMT2A Q03164 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.44
POLB P06746 1/20 0.44
MAPK1 P28482 1/20 0.44
NPC1 O15118 3/20 0.43
HPGD P15428 1/20 0.42
KDM4E B2RXH2 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28432848 0.89 ALDH1A1 (0.52) ATMMAPTALDH1A1AKR1C3RAB9A
SCHEMBL30007458 0.89 ALDH1A1 (0.50) ATMMAPTALDH1A1AKR1C3MEN1
SCHEMBL109891 0.89 ALDH1A1 (0.50) ATMMAPTALDH1A1AKR1C3MEN1
SCHEMBL28684235 0.86 ALDH1A1 (0.49) ATMMAPTALDH1A1AKR1C3MEN1
SCHEMBL28396124 0.85 CDC25B (0.54) CDC25BATMMAPTSMN1; SMN2ALDH1A1
SCHEMBL28410141 0.84 AKR1C3 (0.55) CDC25BATMMAPTALDH1A1AKR1C3
SCHEMBL28648761 0.83 AKR1C3 (0.44) MAPTALDH1A1AKR1C3MEN1LMNA
SCHEMBL9999618 0.82 ALDH1A1 (0.58) ATMMAPTSMN1; SMN2ALDH1A1AKR1C3
SCHEMBL26194148 0.81 ATM (0.60) ATMMAPTSMN1; SMN2ALDH1A1MEN1
SCHEMBL10007412 0.81 ALDH1A1 (0.59) ATMMAPTSMN1; SMN2ALDH1A1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050129859-A1 Curing of coating induced by plasma CIBA CORPORATION 2005-06-16 US disclosed