Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955804 | 0.89 | LMNA (0.60) | SMN1; SMN2LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL28404812 | 0.82 | ALDH1A1 (0.53) | SMN1; SMN2LMNAMAPTCACNA1CABCB1 | |
| SCHEMBL6958184 | 0.81 | CACNA1C (0.50) | SMN1; SMN2LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL6958177 | 0.81 | CACNA1C (0.50) | SMN1; SMN2LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL7421872 | 0.81 | MAPT (0.63) | SMN1; SMN2LMNAMAPTCACNA1CNPC1 | |
| SCHEMBL10749200 | 0.79 | PDE1C (0.49) | SMN1; SMN2LMNAMAPTCACNA1CABCB1 | |
| SCHEMBL11012629 | 0.78 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAMAPTCACNA1CABCB1 | |
| SCHEMBL6960011 | 0.78 | ALDH1A1 (0.54) | SMN1; SMN2MAPTTDP1TSHRCACNA1C | |
| SCHEMBL6960006 | 0.78 | ALDH1A1 (0.54) | SMN1; SMN2MAPTTDP1TSHRCACNA1C | |
| SCHEMBL11007208 | 0.77 | CACNA1C (0.53) | SMN1; SMN2LMNAMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111110854-A | Composition comprising a histamine release-promoting substance and an inhibitory compound | 黄泳华 | 2020-05-08 | — | — | CN | claimed |
| CN-111097050-A | Composition comprising fatty acid or derivative thereof and phenylpyridine derivative | 黄泳华 | 2020-05-05 | — | — | CN | claimed |
| CN-111110854-A | Composition comprising a histamine release-promoting substance and an inhibitory compound | 黄泳华 | 2020-05-08 | — | — | CN | disclosed |
| CN-111097050-A | Composition comprising fatty acid or derivative thereof and phenylpyridine derivative | 黄泳华 | 2020-05-05 | — | — | CN | disclosed |