Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28991825 | 0.88 | MEN1 (0.37) | MAOBCREBBPMEN1KMT2AFFAR1 | |
| SCHEMBL28992050 | 0.88 | MEN1 (0.37) | MAOBCREBBPMEN1KMT2AFFAR1 | |
| SCHEMBL27668304 | 0.82 | MAOB (0.47) | MAOBCASP3SENP8SENP7SENP6 | |
| SCHEMBL27647872 | 0.81 | MAOB (0.46) | MAOBCASP3SENP8SENP7SENP6 | |
| SCHEMBL27770942 | 0.78 | L3MBTL1 (0.46) | MAOBCREBBPMEN1KMT2AMAPT | |
| SCHEMBL560342 | 0.77 | MAOB (0.48) | MAOBCREBBPMEN1KMT2AMAOA | |
| SCHEMBL29498303 | 0.77 | MAOB (0.48) | MAOBCREBBPMEN1KMT2AMAOA | |
| SCHEMBL28543048 | 0.71 | MAOB (0.46) | MAOBCASP3SENP8SENP7SENP6 | |
| SCHEMBL631076 | 0.70 | MAOB (0.48) | MAOBCASP3SENP8SENP7SENP6 | |
| SCHEMBL28801679 | 0.69 | TDP1 (0.35) | CREBBPMEN1KMT2AFFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111298834-A | Preparation method of pharmaceutical intermediate for department of respiration | 孙桂霞 | 2020-06-19 | — | — | CN | claimed |
| CN-111298834-A | Preparation method of pharmaceutical intermediate for department of respiration | 孙桂霞 | 2020-06-19 | — | — | CN | disclosed |
| CN-111298834-A | Preparation method of pharmaceutical intermediate for department of respiration | 孙桂霞 | 2020-06-19 | — | — | CN | disclosed |