SCHEMBL28801679

SCHEMBL28801679

O=CC1COc2c(C(=O)C(O)O)ccc(OCc3ccccc3)c2N1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
FAAH O00519 1/20 0.34
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
CCNB2 O95067 1/20 0.34
CDK1 P06493 1/20 0.34
CDK4 P11802 1/20 0.34
CCNB1 P14635 1/20 0.34
CCND1 P24385 1/20 0.34
CCNB3 Q8WWL7 1/20 0.34
PTGER1 P34995 1/20 0.34
PTGER4 P35408 1/20 0.34
PTGER3 P43115 1/20 0.34
PTGER2 P43116 1/20 0.34
FOLH1 Q04609 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27770942 0.88 L3MBTL1 (0.46) TDP1L3MBTL1MAPTCYP2C9CYP2C19
SCHEMBL27792032 0.86 MEN1 (0.36) TDP1L3MBTL1MAPTCYP2C9CYP2C19
SCHEMBL27815172 0.81 ALDH1A1 (0.33) TDP1L3MBTL1MAPTCYP2C9CYP2C19
SCHEMBL632293 0.77 ADRB1 (0.40) TDP1L3MBTL1MAPTCYP2C9CYP2C19
SCHEMBL27792152 0.76 BRD4 (0.31) L3MBTL1MAPTCCNB2CDK1CDK4
SCHEMBL28411992 0.69 MAOB (0.45) TDP1L3MBTL1MAPTCYP2C9CYP2C19
SCHEMBL28992050 0.67 MEN1 (0.37) SMN1; SMN2FAAHMEN1KMT2ACREBBP
SCHEMBL28991825 0.67 MEN1 (0.37) SMN1; SMN2FAAHALDH1A1MEN1KMT2A
Water SCHEMBL6406913 0.67 ADRB2 (0.39) TDP1L3MBTL1MAPTCYP2C9CYP2C19
SCHEMBL632130 0.67 ADRB2 (0.37) TDP1L3MBTL1MAPTCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102993116-A Preparation method of benzoxazine excitant UNIV CHANGZHOU 2013-03-27 CN claimed