Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17063693 | 1.00 | HPGD (0.39) | HPGDTDP1HSD17B10ALOX15MAPT | |
| SCHEMBL283079 | 0.85 | CYP1A2 (0.39) | HPGDTDP1HSD17B10MAPTRECQL | |
| SCHEMBL2835557 | 0.85 | CYP1A2 (0.39) | HPGDTDP1HSD17B10MAPTRECQL | |
| SCHEMBL22170101 | 0.85 | HSD17B10 (0.50) | HPGDTDP1HSD17B10ALOX15MAPT | |
| SCHEMBL1062422 | 0.85 | CYP1A2 (0.39) | HPGDTDP1HSD17B10MAPTRECQL | |
| SCHEMBL16144679 | 0.85 | HSD17B10 (0.50) | HPGDTDP1HSD17B10ALOX15MAPT | |
| SCHEMBL30849786 | 0.85 | HSD17B10 (0.50) | HPGDTDP1HSD17B10ALOX15MAPT | |
| SCHEMBL29789405 | 0.85 | CYP1A2 (0.39) | HPGDTDP1HSD17B10MAPTRECQL | |
| SCHEMBL31337695 | 0.78 | ALDH1A1 (0.47) | HPGDTDP1HSD17B10ALOX15MAPT | |
| SCHEMBL218996 | 0.76 | HPGD (0.55) | HPGDTDP1HSD17B10ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253420-B | Pyrene compound pH value fluorescent probe and preparation method and application thereof | 中国科学院化学研究所 | 2021-05-04 | — | — | CN | disclosed |
| CN-111253420-A | Pyrene compound pH value fluorescent probe and preparation method and application thereof | 中国科学院化学研究所 | 2020-06-09 | — | — | CN | disclosed |