Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24204652 | 0.86 | CA1 (0.56) | CA1CA2CA12CA7CA9 | |
| SCHEMBL31582796 | 0.81 | ALDH1A1 (0.36) | CA1CA2CA12CA7CA9 | |
| SCHEMBL30676336 | 0.81 | CA9 (0.57) | CA1CA2CA12CA7CA9 | |
| SCHEMBL25707113 | 0.81 | CA9 (0.57) | CA1CA2CA12CA7CA9 | |
| SCHEMBL29970479 | 0.78 | TP53 (0.57) | CA1CA2CA12CA7CA9 | |
| SCHEMBL23409954 | 0.78 | TP53 (0.57) | CA1CA2CA12CA7CA9 | |
| SCHEMBL1717361 | 0.77 | CA12 (0.74) | CA1CA2CA12CA7CA9 | |
| SCHEMBL16239034 | 0.76 | CA12 (0.55) | CA1CA2CA12CA7CA9 | |
| SCHEMBL28412973 | 0.76 | CA1 (0.46) | CA1CA2CA12CA7CA9 | |
| SCHEMBL16008472 | 0.76 | CA12 (0.55) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106644-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ALPHA-V BETA-1 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| CN-111171068-B | Preparation method of silicon spiro-compound | 中国科学院上海有机化学研究所 | 2021-12-14 | — | — | CN | disclosed |
| CN-111171068-A | Preparation method of silicon spiro-compound | 中国科学院上海有机化学研究所 | 2020-05-19 | — | — | CN | disclosed |