Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897364 | 0.84 | ALDH1A1 (0.39) | ALDH1A1ALDH1A3MAPK1ALDH3A1 | |
| SCHEMBL15685409 | 0.79 | HDAC3 (0.30) | — | |
| SCHEMBL19748916 | 0.78 | ALDH1A1 (0.35) | ALDH1A1ALDH1A3MAPK1ALDH3A1 | |
| SCHEMBL29655021 | 0.78 | ALDH1A1 (0.35) | ALDH1A1ALDH1A3MAPK1ALDH3A1 | |
| SCHEMBL29957050 | 0.75 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL3960782 | 0.75 | GAA (0.50) | ALDH1A1ALDH1A3MAPK1ALDH3A1 | |
| SCHEMBL1494366 | 0.70 | GAA (0.36) | ALDH1A1 | |
| SCHEMBL432164 | 0.70 | GAA (0.50) | — | |
| SCHEMBL15709089 | 0.70 | CYP3A4 (0.38) | — | |
| SCHEMBL29851037 | 0.70 | GAA (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320621-B | Indolizine compound and preparation method and application thereof | 中国科学院广州生物医药与健康研究院 | 2022-10-04 | — | — | CN | disclosed |
| CN-111320621-A | Indolizine compound and preparation method and application thereof | 中国科学院广州生物医药与健康研究院 | 2020-06-23 | — | — | CN | disclosed |