Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6735248 | 0.84 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2ERN1KDM1AKDM1B | |
| SCHEMBL19948930 | 0.75 | SRC (0.39) | ALDH1A1SMN1; SMN2KIF11 | |
| SCHEMBL28413293 | 0.75 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL2541967 | 0.75 | HDAC1 (0.40) | ALDH1A1SMN1; SMN2ERN1KIF11 | |
| SCHEMBL9154640 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM1AKDM1B | |
| SCHEMBL9288045 | 0.71 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KIF11 | |
| SCHEMBL25241106 | 0.70 | ALDH1A1 (0.39) | ALDH1A1KDM1AKDM1B | |
| SCHEMBL1042776 | 0.70 | ALDH1A1 (0.39) | ALDH1A1KDM1AKDM1B | |
| SCHEMBL8280034 | 0.70 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KIF11 | |
| SCHEMBL19748916 | 0.70 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |