Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.50 |
| ▸ | ITGAL | P20701 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328915 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2MTNR1AMTNR1BHTR2AMEN1 | |
| SCHEMBL24328927 | 0.90 | KDM4E (0.67) | SMN1; SMN2MTNR1AMTNR1BHTR2AMEN1 | |
| SCHEMBL28418729 | 0.90 | KDM4E (0.67) | SMN1; SMN2MTNR1AMTNR1BHTR2AMEN1 | |
| SCHEMBL24328257 | 0.87 | MEN1 (0.58) | MTNR1AMTNR1BHTR2AMEN1KMT2A | |
| SCHEMBL1460676 | 0.86 | KMT2A (0.61) | MTNR1AMTNR1BHTR2AMEN1KMT2A | |
| SCHEMBL18029114 | 0.86 | KMT2A (0.61) | MTNR1AMTNR1BHTR2AMEN1KMT2A | |
| SCHEMBL1460679 | 0.86 | KMT2A (0.61) | MTNR1AMTNR1BHTR2AMEN1KMT2A | |
| SCHEMBL31370348 | 0.86 | KMT2A (0.61) | MTNR1AMTNR1BHTR2AMEN1KMT2A | |
| SCHEMBL26328524 | 0.85 | MTNR1A (0.55) | MTNR1AMTNR1BHTR2AMEN1KMT2A | |
| SCHEMBL7997808 | 0.83 | HTR2A (0.62) | MTNR1AMTNR1BHTR2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303001-B | Synthesis method of indole mono-substituted 2-hydroxy-3- (1H-indol-3-yl) propionic acid compound | 苏州爱玛特生物科技有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-111303001-A | Synthesis method of indole mono-substituted 2-hydroxy-3- (1H-indol-3-yl) propionic acid compound | 苏州爱玛特生物科技有限公司 | 2020-06-19 | — | — | CN | disclosed |