Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.62 |
| ▸ | HTR2B | P41595 | 2/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25769074 | 0.88 | HTR2A (0.65) | HTR2AHTR2BHTR1AHTR2CMEN1 | |
| SCHEMBL19209536 | 0.87 | HTR2A (0.81) | HTR2AHTR2BHTR1AHTR2CMEN1 | |
| SCHEMBL24328915 | 0.83 | SMN1; SMN2 (0.60) | HTR2AHTR2BHTR1AHTR2CMEN1 | |
| SCHEMBL28413745 | 0.83 | SMN1; SMN2 (0.60) | HTR2AHTR2BHTR1AHTR2CMEN1 | |
| SCHEMBL27911671 | 0.81 | GPR84 (0.75) | HTR2AHTR2BHTR1AHTR2CMEN1 | |
| SCHEMBL24328257 | 0.81 | MEN1 (0.58) | HTR2AHTR2BHTR1AHTR2CMEN1 | |
| SCHEMBL6206125 | 0.80 | MEN1 (0.57) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL24814482 | 0.80 | MTNR1A (0.60) | HTR2AHTR2BHTR1AHTR2CMEN1 | |
| SCHEMBL10956670 | 0.80 | SCN9A (0.65) | HTR2AHTR2BHTR1AHTR2CMEN1 | |
| SCHEMBL1460679 | 0.80 | KMT2A (0.61) | HTR2AHTR2BHTR1AHTR2CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040183-A1 | 1-AMINOALKYL-1H-INDOLES FOR TREATING GLAUCOMA | ALCON UNIVERSAL LTD. (CH) | 2001-06-07 | — | — | WO | disclosed |