SCHEMBL28414434

SCHEMBL28414434

C=C=C.Cc1ccc(CN)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2A6 P11509 1/20 0.52
HRH3 Q9Y5N1 1/20 0.48
LOXL2 Q9Y4K0 4/20 0.46
AGXT P21549 2/20 0.44
IDO1 P14902 2/20 0.44
ABAT P80404 1/20 0.44
PSIP1 O75475 1/20 0.40
ACHE P22303 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NOS3 P29474 1/20 0.40
NOS1 P29475 1/20 0.40
NOS2 P35228 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11699 0.89
SCHEMBL29277663 0.87
Iodide SCHEMBL31425559 0.87 TAAR1 (0.59) TAAR1CYP1A2CYP2A6HRH3LOXL2
Bromide SCHEMBL31513706 0.87 TAAR1 (0.59) TAAR1CYP1A2CYP2A6HRH3LOXL2
Hydrochloric Acid SCHEMBL1938665 0.87 TAAR1 (0.59) TAAR1CYP1A2CYP2A6HRH3LOXL2
Ammonia Solution, Strong SCHEMBL6947334 0.87 TAAR1 (0.59) TAAR1CYP1A2CYP2A6HRH3LOXL2
SCHEMBL260102 0.82 HRH3 (0.74) TAAR1CYP1A2CYP2A6HRH3LOXL2
SCHEMBL11779553 0.81 LOXL2 (0.52) TAAR1CYP1A2CYP2A6HRH3LOXL2
SCHEMBL28196044 0.78 TAAR1 (0.50) TAAR1CYP1A2CYP2A6HRH3LOXL2
P-Xylene SCHEMBL28832784 0.78 ACHE (0.67) CYP2A6IDO1ACHETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111187185-A Method for synthesizing allyl azide derivative 西南民族大学 2020-05-22 CN claimed
CN-111187185-B Method for synthesizing allyl azide derivative 西南民族大学 2022-03-08 CN disclosed
CN-111187185-A Method for synthesizing allyl azide derivative 西南民族大学 2020-05-22 CN disclosed