Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL10653166 | 0.89 | ALDH1A1 (0.58) | ALDH1A1KMT2AALOX15HDAC3HDAC4 | |
| Phthalic Acid SCHEMBL28324781 | 0.89 | ALDH1A1 (0.58) | ALDH1A1KMT2APTK2BALOX15HDAC8 | |
| Phthalic Acid SCHEMBL11906025 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KMT2AALOX15HDAC3HDAC4 | |
| Phthalic Acid SCHEMBL29638858 | 0.88 | ALDH1A1 (0.61) | ALDH1A1KMT2APTK2BALOX15HDAC8 | |
| Phthalic Acid SCHEMBL27934137 | 0.88 | ALDH1A1 (0.61) | ALDH1A1KMT2APTK2BALOX15HDAC8 | |
| Phthalic Acid SCHEMBL185057 | 0.88 | ALDH1A1 (0.61) | ALDH1A1KMT2APTK2BALOX15HDAC8 | |
| Phthalic Acid SCHEMBL8422563 | 0.88 | ALDH1A1 (0.61) | ALDH1A1KMT2APTK2BALOX15HDAC8 | |
| Tetraethylene Glycol SCHEMBL1532572 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KMT2APTK2BALOX15HDAC8 | |
| Tetraethylene Glycol SCHEMBL8578851 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KMT2APTK2BALOX15HDAC8 | |
| Phthalic Acid SCHEMBL28517442 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KMT2APTK2BALOX15HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978909-B | Reactive polyurethane hot melt adhesive for low-temperature coating and preparation method thereof | 北京高盟新材料股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-111303819-B | Low-odor high-initial-adhesion single-component moisture curing reaction type polyurethane hot melt adhesive and preparation method thereof | 北京高盟新材料股份有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-111303819-A | Low-odor high-initial-adhesion single-component moisture curing reaction type polyurethane hot melt adhesive and preparation method thereof | 北京高盟新材料股份有限公司 | 2020-06-19 | — | — | CN | disclosed |