Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL11906025 | 0.98 | ALDH1A1 (0.56) | ALDH1A1ALOX15HDAC3HDAC4HDAC1 | |
| Phthalic Acid SCHEMBL4135702 | 0.94 | GPR84 (0.58) | ALDH1A1ALOX15HDAC3HDAC4HDAC1 | |
| Phthalic Acid SCHEMBL30480760 | 0.94 | ALDH1A1 (0.67) | ALDH1A1ALOX15HDAC3HDAC4HDAC1 | |
| Phthalic Acid SCHEMBL1906918 | 0.94 | ALDH1A1 (0.67) | ALDH1A1ALOX15HDAC3HDAC4HDAC1 | |
| Phthalic Acid SCHEMBL11229408 | 0.93 | HDAC3 (0.55) | ALDH1A1ALOX15HDAC3HDAC4HDAC1 | |
| Terephthalic Acid SCHEMBL11905415 | 0.93 | ALDH1A1 (0.50) | ALDH1A1ALOX15HDAC3HDAC4HDAC1 | |
| Phthalic Acid SCHEMBL28192595 | 0.92 | GPR84 (0.61) | ALDH1A1ALOX15HDAC3HDAC4HDAC1 | |
| Sebacic Acid SCHEMBL8362100 | 0.91 | ALDH1A1 (0.64) | ALDH1A1ALOX15HDAC3HDAC4HDAC1 | |
| Phthalic Acid SCHEMBL11905486 | 0.91 | ALDH1A1 (0.64) | ALDH1A1ALOX15HDAC8MAPTSMN1; SMN2 | |
| Phthalic Acid SCHEMBL11709147 | 0.91 | ALDH1A1 (0.64) | ALDH1A1ALOX15HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206727-A | Degradable copolyester and preparation method thereof | 中国科学院理化技术研究所 | 2024-06-18 | — | — | CN | disclosed |
| CN-118165235-A | Degradable copolyester and preparation method thereof | 中国科学院理化技术研究所 | 2024-06-11 | — | — | CN | disclosed |
| CN-108175716-B | Process for preparing hollow polyurethane microspheres and photoprotective cosmetic compositions comprising same | 万华化学集团股份有限公司 | 2020-12-15 | — | — | CN | disclosed |
| CN-108192074-B | Preparation method of crosslinked polyurethane microspheres and/or polyurethane hollow microspheres | 万华化学集团股份有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-106398625-B | Oil chemical resistant article and oil chemical resistant moisture curable hot melt adhesive composition | H.B.富乐公司 | 2019-12-27 | — | — | CN | disclosed |
| CN-105849599-B | Cellulose ester membrane, its manufacturing method and polarizer | 柯尼卡美能达株式会社 | 2018-06-15 | — | — | CN | disclosed |
| CN-104870352-B | Optical film roll, method for producing same, polarizing plate, and display device | 柯尼卡美能达株式会社 | 2017-03-22 | — | — | CN | disclosed |
| CN-105849599-A | Cellulose-ester film, manufacturing method therefor, and polarizing plate | 柯尼卡美能达株式会社 | 2016-08-10 | — | — | CN | disclosed |
| CN-104870352-A | Optical film roll, method for producing same, polarizing plate, and display device | KONICA MINOLTA INC | 2015-08-26 | — | — | CN | disclosed |
| US-9110243-B2 | Laminate film, optically compensatory film, polarizing plate, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2015-08-18 | — | — | US | disclosed |
| US-20120251781-A1 | LAMINATE FILM, OPTICALLY COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2012-10-04 | — | — | US | disclosed |
| EP-0296098-A2 | Crosslinked polyurethane emulsion, process and prepolymer for its production and process for forming coatings from said emulsion | W.R. Grace & Co.-Conn. (US) | 1988-12-21 | — | — | EP | disclosed |
| US-4569981-A | Solid, water-dispersible plastics precursors containing isocyanate groups, a process for the production of aqueous plastics dispersions using such plastics precursors | BAYER AKTIENGESELLSCHAFT (DE) | 1986-02-11 | — | — | US | disclosed |
| US-4544683-A | GYPSUM-POLYURETHANE OR POLYURETHANE-POLYUREA | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-01 | — | — | US | disclosed |
| US-4543144-A | CROSSLINKING WITH A BLOCKES POLYISOCYANATE OR FORMADEHYDE RESIN | BAYER AKTIENGESELLSCHAFT (DE) | 1985-09-24 | — | — | US | disclosed |
| US-4331717-A | NEUTRALIZATION OF TERTIARY NITROGEN ATOMS WITH ORGANIC ACID, CORROSION RESISTANCE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-25 | — | — | US | disclosed |
| US-4292226-A | Process for the production of aqueous dispersions or solutions of polyurethane polyureas, and dispersions or solution obtainable by this process and their use | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-29 | — | — | US | disclosed |
| US-4186118-A | Process for the preparation of modified aqueous synthetic resin dispersions | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-29 | — | — | US | disclosed |
| US-4182828-A | Production of solutions or dispersions of polyisocyanate polyaddition products containing urethane and/or urea groups and containing both anionic and cationic groups | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-08 | — | — | US | disclosed |
| US-3943252-A | Polyurethane casein coating composition | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-09 | — | — | US | disclosed |