Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | PTPRA | P18433 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328923 | 1.00 | SMN1; SMN2 (0.65) | SMN1; SMN2HTR2ANR3C1ADRB3KDM4E | |
| SCHEMBL28409196 | 0.89 | SMN1; SMN2 (0.65) | SMN1; SMN2HTR2ANR3C1KDM4EMAPT | |
| SCHEMBL24328359 | 0.89 | SMN1; SMN2 (0.65) | SMN1; SMN2HTR2ANR3C1KDM4EMAPT | |
| SCHEMBL12039399 | 0.86 | KDM4E (0.68) | SMN1; SMN2HTR2ANR3C1ADRB3KDM4E | |
| SCHEMBL503548 | 0.84 | KMT2A (0.66) | HTR2ANR3C1KDM4EMAPTAPAF1 | |
| SCHEMBL29809822 | 0.84 | KMT2A (0.66) | HTR2ANR3C1KDM4EMAPTAPAF1 | |
| SCHEMBL503549 | 0.84 | KMT2A (0.66) | HTR2ANR3C1KDM4EMAPTAPAF1 | |
| SCHEMBL31036029 | 0.84 | KMT2A (0.66) | HTR2ANR3C1KDM4EMAPTAPAF1 | |
| SCHEMBL8769008 | 0.84 | KMT2A (0.66) | HTR2ANR3C1KDM4EMAPTAPAF1 | |
| SCHEMBL24328361 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2HTR2AADRB3KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303001-B | Synthesis method of indole mono-substituted 2-hydroxy-3- (1H-indol-3-yl) propionic acid compound | 苏州爱玛特生物科技有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-111303001-A | Synthesis method of indole mono-substituted 2-hydroxy-3- (1H-indol-3-yl) propionic acid compound | 苏州爱玛特生物科技有限公司 | 2020-06-19 | — | — | CN | disclosed |