Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328359 | 1.00 | SMN1; SMN2 (0.65) | SMN1; SMN2MTNR1AMTNR1BHTR2AHTR1D | |
| SCHEMBL28414749 | 0.89 | SMN1; SMN2 (0.65) | SMN1; SMN2HTR2AKDM4EMAPTLMNA | |
| SCHEMBL24328923 | 0.89 | SMN1; SMN2 (0.65) | SMN1; SMN2HTR2AKDM4EMAPTLMNA | |
| SCHEMBL11942138 | 0.86 | KDM4E (0.68) | SMN1; SMN2MTNR1AMTNR1BHTR2AHTR1D | |
| SCHEMBL30406433 | 0.84 | KMT2A (0.73) | MTNR1AMTNR1BHTR2AHTR1DKDM4E | |
| SCHEMBL29527694 | 0.84 | KMT2A (0.73) | MTNR1AMTNR1BHTR2AHTR1DKDM4E | |
| SCHEMBL7614399 | 0.84 | KMT2A (0.73) | MTNR1AMTNR1BHTR2AHTR1DKDM4E | |
| SCHEMBL41266 | 0.84 | KMT2A (0.73) | MTNR1AMTNR1BHTR2AHTR1DKDM4E | |
| SCHEMBL21055755 | 0.84 | MTNR1A (0.53) | SMN1; SMN2MTNR1AMTNR1BHTR2AHTR1D | |
| SCHEMBL41267 | 0.84 | KMT2A (0.73) | MTNR1AMTNR1BHTR2AHTR1DKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303001-B | Synthesis method of indole mono-substituted 2-hydroxy-3- (1H-indol-3-yl) propionic acid compound | 苏州爱玛特生物科技有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-111303001-A | Synthesis method of indole mono-substituted 2-hydroxy-3- (1H-indol-3-yl) propionic acid compound | 苏州爱玛特生物科技有限公司 | 2020-06-19 | — | — | CN | disclosed |