Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | BLM | P54132 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | MPO | P05164 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | PTPRA | P18433 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769008 | 1.00 | KMT2A (0.66) | KMT2AKDM4EMAPTBLMLMNA | |
| SCHEMBL29809822 | 1.00 | KMT2A (0.66) | KMT2AKDM4EMAPTBLMLMNA | |
| SCHEMBL31036029 | 1.00 | KMT2A (0.66) | KMT2AKDM4EMAPTBLMLMNA | |
| SCHEMBL503549 | 1.00 | KMT2A (0.66) | KMT2AKDM4EMAPTBLMLMNA | |
| SCHEMBL24113516 | 0.89 | SCN9A (0.59) | KMT2AKDM4EMAPTBLMLMNA | |
| SCHEMBL41266 | 0.89 | KMT2A (0.73) | KMT2AKDM4EMAPTBLMLMNA | |
| SCHEMBL30310502 | 0.89 | SCN9A (0.59) | KMT2AKDM4EMAPTBLMLMNA | |
| SCHEMBL16975865 | 0.89 | HTR2A (0.55) | KMT2AKDM4EMAPTBLMLMNA | |
| SCHEMBL41267 | 0.89 | KMT2A (0.73) | KMT2AKDM4EMAPTBLMLMNA | |
| SCHEMBL29527694 | 0.89 | KMT2A (0.73) | KMT2AKDM4EMAPTBLMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 965 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144842-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TRYPTOPHAN AND PHYLLOKININ DERIVATIVE FOR USE IN TREATING PSYCHIATRIC AND PSYCHOLOGICAL CONDITIONS | TEMPLE OTORONGO LLC (US) | 2026-05-28 | — | — | US | claimed |
| US-12600699-B2 | Thiosemicarbazates and uses thereof | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-04-14 | — | — | US | claimed |
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2025-07-08 | — | — | US | claimed |
| WO-2025109003-A1 | P-CADHERIN LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2025-05-30 | — | — | WO | claimed |
| CN-118406439-B | Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing | 万华化学集团电子材料有限公司 | 2024-10-18 | — | — | CN | claimed |
| EP-4274838-B1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS | BICYCLETX LTD (GB) | 2024-09-25 | — | — | EP | claimed |
| CN-118406439-A | Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing | 万华化学集团电子材料有限公司 | 2024-07-30 | — | — | CN | claimed |
| CN-118184756-A | Engineered Leptospira perfoliatum lectin mutant and application thereof | 浙江大学医学院附属第一医院(浙江省第一医院) | 2024-06-14 | — | — | CN | claimed |
| US-20240108738-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS | BICYCLETX LIMITED (GB) | 2024-04-04 | — | — | US | claimed |
| US-11904020-B2 | Bicyclic peptide ligands specific for TREM2 | BICYCLETX LIMITED (GB) | 2024-02-20 | — | — | US | claimed |
| EP-1372571-A4 | METHOD AND COMPOSITIONS FOR OPTIMIZING BLOOD AND TISSUE STABILITY OF CAMPTOTHECIN AND OTHER ALBUMIN-BINDING THERAPEUTIC COMPOUNDS | NEW CENTURY PHARMACEUTICALS (US) | 2006-06-07 | — | — | EP | claimed |
| WO-2005097820-A1 | PEPTIDES FOR INHIBITING MDM2 FUNCTION | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2005-10-20 | — | — | WO | claimed |
| EP-1372571-A2 | METHOD AND COMPOSITIONS FOR OPTIMIZING BLOOD AND TISSUE STABILITY OF CAMPTOTHECIN AND OTHER ALBUMIN-BINDING THERAPEUTIC COMPOUNDS | New Century Pharmaceuticals, Inc. (US) | 2004-01-02 | — | — | EP | claimed |
| US-20020193318-A1 | Methods and compositions for optimizing blood and tissue stability of camptothecin and other albumin-binding therapeutic compounds | NEW CENTURY PHARMACEUTICALS, INC. | 2002-12-19 | — | — | US | claimed |
| WO-2002074246-A2 | METHOD AND COMPOSITIONS FOR OPTIMIZING BLOOD AND TISSUE STABILITY OF CAMPTOTHECIN AND OTHER ALBUMIN-BINDING THERAPEUTIC COMPOUNDS | NEW CENTURY PHARMACEUTICALS, INC. (US) | 2002-09-26 | — | — | WO | claimed |
| EP-1101823-A2 | Process for the preparation of indigo derivatives and dyes for ceratinous fibers containing the same | Wella Aktiengesellschaft (DE) | 2001-05-23 | — | — | EP | claimed |
| US-5034318-A | Culturing Coryneform glutamic acid producing bacteria with plasmids | AJINOMOTO CO., INC. (JP) | 1991-07-23 | — | — | US | claimed |
| EP-0136359-A1 | PROCESS FOR PREPARING L-HISTIDINE | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1985-04-10 | — | — | EP | claimed |
| US-4371614-A | E.Coli bacteria carrying recombinant plasmids and their use in the fermentative production of L-tryptophan | AJINOMOTO CO., INC. (JP) | 1983-02-01 | — | — | US | claimed |
| US-3930948-A | ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES | AJINOMOTO CO., INC. (JA) | 1976-01-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | DNPEP, NPEPPS, PAM | KMT2A 1848/4885KDM4E 3819/4885MAPT 1350/4885 |
| US-11904020-B2 | Bicyclic peptide ligands specific for TREM2 | APP, TIMCC, ADM2 | KMT2A 3481/4885KDM4E 4811/4885MAPT 308/4885 |
| US-20260144842-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TRYPTOPHAN AND PHYLLOKININ DERIVATIVE FOR USE IN TREATING PSYCHIATRIC AND PSYCHOLOGICAL CONDITIONS | OPRK1, TPH1, HTR3C | KMT2A 4104/4885KDM4E 4515/4885MAPT 1093/4885 |
| US-20240108738-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS | PBK, KLRK1, MICA | KMT2A 1977/4885KDM4E 1930/4885MAPT 4099/4885 |
| US-12600699-B2 | Thiosemicarbazates and uses thereof | MET, THRB, ABAT | KMT2A 2188/4885KDM4E 2649/4885MAPT 1679/4885 |
| US-20020193318-A1 | Methods and compositions for optimizing blood and tissue stability of camptothecin and other albumin-binding therapeutic compounds | ALB, TYMP, SHBG | KMT2A 3823/4885KDM4E 3521/4885MAPT 670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.